DNA/RNA Defend™
- stabilizes RNA
- stabilizes DNA
- inactivation of pathogens
- lysis buffer
- mucolytic
DNA/RNA Defend™ (DRD) is the RUO and colorless version of InActiv Blue®, a guanidine-based medium for pathogen inactivation, stabilization of DNA and RNA, and lysis of biological samples. Requires nucleic acid extraction. DNA/RNA Defend™ (DRD) is a cost-effective and superior alternative to similar buffers on the market.
Perfect stability of nucleic acids in complex biomaterials without freezing
DNA/RNA Defend™ protects nucleic acids during transport and storage, even up to 37 °C for one month. Complex samples like tissues, swab, saliva, blood, urine, oral fluid, milk and stool are perfectly stabilized. The buffer is also your trusted ally against freeze-thaw damage and for the long-term preservation of biological samples. Notably, the buffer completely inactivates pathogens, ensuring the safe handling of biological specimens.
Stability of viral particles stored in buffer at room temperature for up to 30 days
No Data Found
RT-qPCR results for SARS-CoV-2 E-gene in DNA/RNA Defend buffer spiked with low or high viral titer and stored in the fridge (4 °C) or at room temperature (RT) for 30 days (n=12).
Freeze-thaw stability (n=6)
No Data Found
Buffer with nasopharygeal swab samples inoculated with high and low viral titer were exposed to 5 freeze-thaw cycles, followed by RNA extraction and RT-qPCR
Stability of RNA in urine for up to 9 days at 37 °C
RT-qPCR results for KLK3 gene on RNA extracted from urine of 3 healthy donors spiked with LNCaP cells and stabilized with DNA/RNA Defend buffer.
Similar results for HOXC6 and DLX1 (not shown). Data courtesy of mdxhealth.
Protection of blood RNA
DNA/RNA Defend™ protects RNA when keeping biomaterials stored at room temperature, even for the most complex sample types such as whole blood and saliva.
